Principles of Inheritance and Variation TS

Which of the following father and son duos received Nobel Prize ?

The famous double helix model of DNA was proposed by Watson and Crick in _______ and they shared Nobel Prize for Physiology or Medicine in _______ for their effort.

The branch of biology that deals with inheritance, as well as the variation of characters from parents to offspring, is called as :

A plant, on repeated self-pollination, preserves the trait expressed for many generations. Such a plant is said to be :

Which of the following is a recessive trait for a character chosen by Mendel in garden pea ?

Which of the following was not a character studied by Mendel in garden pea ?

The \( F_1 \) progeny in monohybrid crosses by Mendel resembled :

The units of inheritance according to Mendel were ‘factors’. Today these factors are known as :

Genes that code for a pair of contrasting traits or slightly different forms of the same gene are known as :

In true breeding, the allelic pair of genes are :

What could be the genotype of a garden pea plant that expresses the tall trait of height ?

In a dissimilar situation, the unit factor that expresses itself is called as :

A genetic cross between homozygous individuals but with different alleles for a single gene of interest is called as :

A plant with the genotype Tt should be called :

A graphical representation to calculate the probability of all possible genotypes of offspring in a genetic cross is called as :

The \(  F_2 \)  genotypic ratio of a monohybrid cross is :
\(
\begin{array}{|l|l|l|l|}
\hline 1 . & 1: 1 & 2 . & 3: 1 \\
\hline 3 . & 1: 2: 1 & 4 . & 9: 7 \\
\hline
\end{array}
\)

On self-pollinated a tall \( F_2 \) plant, the progeny can be:

What is the \( F_2 \) phenotypic ratio in cases of incomplete dominance?
\(
\begin{array}{|l|l|l|l|}
\hline 1 . & 1: 1 & 2 . & 3: 1 \\
\hline 3 . & 1: 2: 1 & 4 . & 1: 1 \\
\hline
\end{array}
\)

What is the \( F_2 \) genotypic ratio in cases of incomplete dominance?
\(
\begin{array}{|l|l|l|l|}
\hline 1 . & 1: 1 & 2 . & 3: 1 \\
\hline 3 . & 1: 2: 1 & 4 . & 1: 1 \\
\hline
\end{array}
\)

The ultimate source of allelic variation is:

In complete dominance, the recessive allele with respect to the dominant allele:

In the case of co-dominance, the \( F_1 \) generation resembles:

Blood group antigens are:

[/latex]
\(
\text { The inheritance of } \mathrm{I}^{\mathrm{A}} \text { and } \mathrm{I}^{\mathrm{B}} \text { allele exhibit: }
\)

The number of alleles, the genotypic combinations, and phenotypes in the ABO system are respectively:

What can the possible blood groups of progeny whose father and mother are of A and B blood groups, respectively ?

What can be the blood groups of progeny whose father and mother are of AB and O blood groups, respectively ?

Theoretically, what can be the maximum number of alleles a particular gene can have ?

Suppose a gene has seven alleles. What would be the number of alleles in an individual at any instant ?

To study whether a gene exhibits multiple allelism or not, one must study :

Occasionally, a single gene product may produce more than one effect. Such a gene is said to be:

The mechanism of sex determination in grasshoppers is :

A woman receives her X chromosomes from :

In humans, the mechanism of sex determination is :

Identify the incorrect statement :

Pedigree analysis is used for genetic analysis in humans rather than conventional genetic methods because :
\(
\begin{aligned}
&\begin{array}{|l|l|}
\hline \text { I. } & \text { Choice matings are not possible. } \\
\hline \text { II. } & \text { The number of progeny is limited. } \\
\hline
\end{array}\\
&\text { Of the two statements: }
\end{aligned}
\)

Mendelian disorders are mainly determined by :

Which of the following is not an X – linked recessive disorder in humans ? 

Thalassemia is inherited as a/an _____ condition.

A human female who is not color blind but whose father was color blind marries a normal male. What proportion of their male progeny will have red-green color blindness ?

The source of any of the genes located on either of the X chromosomes in a female cannot be :

Haemophilia is inherited as a/an ______ condition.

What is incorrect for Hemophilia ?

The family pedigree of Queen Victoria shows a number of haemophilic descendants as she was :

Sickle cell anaemia results from :

The point mutation in sickle cell anaemia leads to a change in the codon. Identify the correct change :

Which of the following amino acid substitution in the beta chain of the haemoglobin molecule leads to the development of sickle cell anaemia ?

In sickle cell anaemia, the mutant haemoglobin molecule undergoes :

Regarding Thalessmia:-

\(
\begin{array}{|l|l|}
\hline \begin{array}{l}
\text { Statement } \\
\text { I: }
\end{array} & \begin{array}{l}
\text { It is an autosome-linked recessive blood } \\
\text { disease transmitted from parents to the } \\
\text { offspring when both partners are the } \\
\text { unaffected carriers for the gene (or } \\
\text { heterozygous). }
\end{array} \\
\hline \begin{array}{l}
\text { Statement } \\
\text { II: }
\end{array} & \begin{array}{l}
\text { The defect could be due to either mutation or } \\
\text { deletion which ultimately results in a reduced } \\
\text { rate of synthesis of one of the globin chains ( } \alpha \\
\text { and } \beta \text { chains) that make up haemoglobin. }
\end{array} \\
\hline
\end{array}
\)

Mutations that arise due to changes in a single base pair of DNA are called as :

In cases of Phenylketonuria :

What is the mode of inheritance phenylketonuria ?

In Phenylketonuria,

\(
\begin{array}{|l|l|}
\hline \text { I. } & \begin{array}{l}
\text { Phenylpyruvic acid and other derivatives are } \\
\text { accumulated in the brain resulting in mental } \\
\text { retardation. }
\end{array} \\
\hline \text { II. } & \begin{array}{l}
\text { These are also excreted through urine because of their } \\
\text { poor absorption by the kidney. }
\end{array} \\
\hline
\end{array}
\)

When there is a change in the chromosome number such that the changes number is not an exact multiple of base number [haploid number], the condition is called as:

Thalassemia can be classified according to which chain of the haemoglobin molecule is affected.
\(
\begin{array}{|l|l|}
\hline \begin{array}{l}
\text { Statement } \\
\text { I: }
\end{array} & \begin{array}{l}
\alpha \text { Thalassemia is controlled by a single gene } \\
\text { HBB on chromosome 11 of each parent and } \\
\text { occurs due to mutation of one or both the } \\
\text { genes. }
\end{array} \\
\hline \begin{array}{l}
\text { Statement } \\
\text { II: }
\end{array} & \begin{array}{l}
\beta \text { Thalassemia is controlled by two closely } \\
\text { linked genes HBA1 and HBA2 on } \\
\text { chromosome 16 of each parent. }
\end{array} \\
\hline
\end{array}
\)

What will be true regarding the comparison of thalassemia and sickle cell anaemia ?

Failure of cytokinesis after telophase stage of cell division results in an increase in a whole set of chromosomes in an organism and this phenomenon is known as :

Which of the following is not a feature of Down’s Syndrome ?

An individual affected by Klinefelter’s syndrome:

An individual affected with Turner’s Syndrome:
I. Is a female
II. Has 45 chromosomes
III. Has rudimentary ovaries
Of the above statements, the correct statements are: