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The definition of hormone describes them as having all the following features except:
(b)
The only hormone secreted by pars intermedia of hypophysis is:
(a)
All the following hormones are produced by anterior pituitary except:
(d)
ADH and oxytocin are synthesized by:
(b)
Which of the following endocrine glands is under direct neural regulation of hypothalamus?
(c)
All the following hormones are produced by anterior pituitary except:
(a)
Graves‘ disease is characterized by all the following except:
(d)
Graves’ disease is an autoimmune disorder that leads to hyperthyroidism — an overactive thyroid. Key features include:
So, “weight gain” is not characteristic of Graves’ disease.
Functions of glucagon do not include:
(c)
The functions regulated or influenced by thyroid glands in humans include all except:
(d)
Which of the following cannot be regarded as a main function of cortisol?
(c)
The actions of adrenaline will include all the following except:
(c)
3. Glycogenesis
❌ Incorrect – Adrenaline inhibits glycogenesis (formation of glycogen) and promotes glycogenolysis (breakdown of glycogen to glucose) to increase blood glucose levels.
So this action is not associated with adrenaline — hence the correct answer.
4. Positive ionotropic and chronotropic effect on heart
✅ Correct – Adrenaline increases heart rate (chronotropic) and force of contraction (ionotropic).
Diabetes insipidus, characterized by water loss and dehydration, is caused by:
(a)
What would not be true for pancreas?
(b)
❌ “The endocrine islets of Langerhans constitute about 50%50\%50% of the gland”
Incorrect – The islets of Langerhans constitute only 1–2% of the total pancreatic mass, not 50%.
The majority (~98–99%) of the pancreas is exocrine in nature.
\(
\begin{aligned}
& \text { Glycosuria and ketonuria are diagnostic of: }\\
&\begin{array}{|l|l|}
\hline \text { 1. Graves’ disease } & \text { 2. Addison’s disease } \\
\hline \text { 3. Conn’s syndrome } & \text { 4. Diabetes mellitus } \\
\hline
\end{array}
\end{aligned}
\)
(d)
Adenohypophysis is an endocrine gland that secrets all the following except:
(c)
The major portion of the posterior lobe of the pituitary gland is called as:
(b)
The peptide thyroid hormone that lowers calcium and phosphate ion concentration in the blood is:
(c)
Match each item in Column I [zones of adrenal cortex] with one in Column II [hormone produced] and select your answer from the codes given:
\(
\begin{array}{|l|l|l|l|}
\hline & \text { COLUMN I } & & \text { COLUMN II } \\
\hline \text { A. } & \text { Zona glomerulosa } & \text { a. } & \text { Aldosterone } \\
\hline \text { B. } & \text { Zona fasciculata } & \text { b. } & \text { Cortisol } \\
\hline \text { C. } & \text { Zona reticularis } & \text { c. } & \text { Adrenal androgens } \\
\hline
\end{array}
\)
Codes:
\(
\begin{array}{|l|l|l|l|}
\hline & \text { A } & \text { B } & \text { C } \\
\hline 1 . & \text { a } & \text { b } & \text { c } \\
\hline 2 . & \text { a } & \text { c } & \text { b } \\
\hline 3 . & \text { b } & \text { a } & \text { c } \\
\hline 4 . & \text { b } & \text { c } & \text { a } \\
\hline
\end{array}
\)
(a)
What term/s would describe adrenaline and noradrenaline?
(c)
Which of the following has both exocrine and endocrine functions?
(a)
Which of the following is sometimes also called as the ‘birth‘ hormone?
(c)
During pregnancy, the deficiency of which of the following can cause defective development and maturation of the growing baby leading to stunted growth, mental retardation, abnormal skin and deafmutism?
(c)
Identify the correct statements from the following:
I. ANF is secreted by the right atrium of heart and causes vasodilation.
II. Erythropoietin is secreted by kidney and stimulates bone marrow to produce RBC.
III. Insulin-like growth factors are secreted by liver and play an important role in childhood growth, and has anabolic effects in adults.
(d)
Which pair of hormones will both bind to membrane bound receptors located on its target cells?
(b)
Hormones which interact with intracellular receptors:
(d)
Some hormones can act on their target cells through second messengers. Identify the one that does not:
(a)
All the following chemicals are steroids except:
(a)
A decrease in blood glucose is most likely to result in:
(d)
Explanation:
When blood glucose levels decrease, the body responds through hormonal regulation to restore homeostasis.
Here’s the correct physiological sequence:
Decrease in blood glucose is sensed by the alpha cells of the pancreas.
This leads to increased secretion of glucagon.
Glucagon acts primarily on the liver, stimulating:
Glycogenolysis: breakdown of stored glycogen into glucose.
Gluconeogenesis: synthesis of new glucose from non-carbohydrate sources.
The newly released glucose enters the bloodstream, restoring glucose levels.
When dehydration occurs, the response of the human body would be that:
(a)
GnRH , a hypothalamic hormone, needed in reproduction, acts on the
(b)
The posterior pituitary gland is not a ‘true‘ endocrine gland because
(b)
A chemical signal that has both endocrine and neural roles is
(c)
Which gland decreases in size with increasing age
(c)
Which of the following hormones is responsible for both the milk ejection reflex and the foetal ejection reflex?
(c)
Artificial light, extended work-time and reduced sleep-time disrupt the activity of
(b)
Which of the following conditions will stimulate parathyroid gland to release parathyroid hormone?
(b)
Match the follwing columns and select the correct option.
\(
\begin{array}{|l|l|l|l|}
\hline \text { (a) } & \text { Pituitary gland } & \text { (i) } & \text { Grave’s disease } \\
\hline \text { (b) } & \text { Thyroid gland } & \text { (ii) } & \text { Diabetes mellitus } \\
\hline \text { (c) } & \text { Adrenal gland } & \text { (iii) } & \text { Diabetes insipidus } \\
\hline \text { (d) } & \text { Pancreas } & \text { (iv) } & \text { Addison’s disease } \\
\hline
\end{array}
\)
Options:
\(
\begin{array}{|l|l|l|l|l|}
\hline & \text { (a) } & \text { (b) } & \text { (c) } & \text { (d) } \\
\hline 1 . & \text { (iii) } & \text { (ii) } & \text { (i) } & \text { (iv) } \\
\hline 2 . & \text { (iii) } & \text { (i) } & \text { (iv) } & \text { (ii) } \\
\hline 3 . & \text { (ii) } & \text { (i) } & \text { (iv) } & \text { (iii) } \\
\hline 4 . & \text { (iv) } & \text { (iii) } & \text { (i) } & \text { (ii) } \\
\hline
\end{array}
\)
(b)
Hypothalamus secretes the releasing hormones and the inhibitory hormones into:
(c)
Melatonin:
(d)
ACTH controls the secretion of …………..?
(a)
A temporary endocrine gland in the human body is?
(c)
Which gastrointestinal hormone acts on the exocrine pancreas and stimulates secretion of water and bicarbonate ions?
(b)
Which of the following clinical feature is unlikely to be seen in hypothyroidism?
(c)
A young child shows stunted growth and mental retardation. You would like to check the levels of:
(a)
Which of the following is not related with thymosins?
(d)
Thymosin production actually decreases with age due to thymic involution. As the thymus atrophies post-puberty and especially in older adults, thymosin levels drop, which contributes to weaker immunity .
Thymosins are produced by the thymus gland, not the thyroid gland
Adrenal cortex is composed of 3 layers. The sequence of layers from the outside to the inside is:-
(a)
Go through the following points
I. Regulate the development, maturation and functions of epididymis, vas deferens, seminal vesicle, prostrate gland
urethra, etc.
II. Stimulate muscular growth of facial and axillary hairs, aggressiveness, low pitch of voice, etc.
III. Stimulates spermatogenesis
IV. Act on CNS and sexual behaviour (libido)
V. Produce anabolic (synthetic) effect on protein and carbohydrate metabolism
VI. The Leydig’s cell/ interstitial cells (present in intertubular space) secrete this hormone under the influence of LH.
Above points are associated with ____ hormones
(c)
Which of the following statements is incorrect?
(b)
Progesterone:-
(d)
Match each hormone (Column – I) with its effect on target cells (Column – II) and the gland where it is produced (Column – III)-
\(
\begin{array}{|l|l|l|}
\hline
\textbf{Column I} & \textbf{Column II} & \textbf{Column III} \\
\hline
1.\ \text{Thyroxine} & E.\ \text{Regulate metabolism} & W.\ \text{Thyroid gland} \\
\hline
2.\ \text{Insulin} & A.\ \text{Lowers blood glucose} & U.\ \text{Pancreas} \\
\hline
3.\ \text{PTH} & G.\ \text{Raises blood Ca}^{2+}\text{ level} & R.\ \text{Parathyroid gland} \\
\hline
4.\ \text{Epinephrine} & C.\ \text{Triggers “fight or flight”} & S.\ \text{Adrenal medulla} \\
\hline
5.\ \text{Melatonin} & F.\ \text{Related to daily rhythm} & P.\ \text{Pineal gland} \\
\hline
6.\ \text{ADH} & H.\ \text{Boost water retention} & T.\ \text{Hypothalamus (stored in posterior pituitary)} \\
\hline
7.\ \text{Androgen} & D.\ \text{Promotes male traits} & Q.\ \text{Testes} \\
\hline
8.\ \text{FSH} & B.\ \text{Stimulates ovary/testes} & V.\ \text{Anterior pituitary} \\
\hline
\end{array}
\)
\(
\begin{aligned}
& 1-\text { E, W; } 2-\text { A, U; } 3-\text { G, R; } 4-\text { C, S; } 5-\text { F, P; } 6-\text { H, T; } 7-\text { D, Q; } 8-\text { B, V } \\
& 1-\text { E, W; } 2-\text { A; R; } 3-\text { V, R; } 4-\text { C, U; } 5-\text { F, T; } 6-\text { H, S; } 7-\text { D, Q; } 8-\text { B, P } \\
& 1-\text { B, V; } 2-\text { E, U; } 3-\text { G, W; } 4-\text { C, S; } 5-\text { A, P; } 6-\text { H, T; } 7-\text { D, Q; } 8-\text { F, R } \\
& 1-\text { A, W; } 2-\text { C, U; } 3-\text { G, R; } 4-\text { E, S; } 5-\text { F, P; } 6-\text { H, T; } 7-\text { D, Q; } 8-\text { B, V }
\end{aligned}
\)
(a)
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