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Read the given statements and select the correct option.
Statement 1: Respiration is most efficient in the insects, among the invertebrates.
Statement 2: In the insects, air is carried directly to the cells by tracheoles.
(a) Lower invertebrates like sponges, coelenterates, flatworms, etc., exchange \(\mathrm{O}_2\) with \(\mathrm{CO}_2\) by simple diffusion over their entire body surface. Earthworms use their moist cuticle and insects have a network of tubes (tracheal tubes) to transport atmospheric air within the body.Â
Read the given statements characterising certain types of animals. Select the option which correctly exemplifies each of these types.
(i) Animal having external gills
(ii) Animal having internal gills
(iii) Animal showing tracheal respiration
(iv) Animal revealing buccopharyngeal respiration
\(
\begin{array}{|l|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } & \text { (iv) } \\
\hline \text { (a) } & \text { Prawn } & \text { Arenicola } & \text { Unio } & \text { Fish } \\
\hline \text { (b) } & \text { Necturus } & \text { Unio } & \text { Prawn } & \text { Frog } \\
\hline \text { (c) } & \text { Pila } & \text { Arenicola } & \text { Unio } & \text { Toad } \\
\hline \text { (d) } & \text { Necturus } & \text { Pila } & \text { Millipede } & \text { Toad } \\
\hline
\end{array}
\)
Necturus (Mud puppy, Amphibia) possesses three pairs of external gills. Pila (Apple snail, Mollusca) respires by means of gills (ctenidium) in water and by a pulmonary sac on land. Millipedes (Arthropoda) respire by tracheae (tracheal respiration) and toads (Amphibia) exhibit buccopharyngeal respiration.
Match column I with column II and select the correct option from the given codes.
\(
\begin{array}{|c|l|c|l|}
\hline & \begin{array}{l}
\text { Column I } \\
\text { (Animals) }
\end{array} & & \begin{array}{l}
\text { Column II } \\
\text { (Respiratory structures) }
\end{array} \\
\hline \text { A. } & \text { Pigeon } & \text { (i) } & \text { Book gills } \\
\hline \text { B. } & \text { Scorpion } & \text { (ii) } & \text { Pharyngeal wall } \\
\hline \text { C. } & \text { Planaria } & \text { (iii) } & \text { Lungs } \\
\hline \text { D. } & \text { Earthworm } & \text { (iv) } & \text { Gills } \\
\hline \text { E. } & \text { Spiders } & \text { (v) } & \text { Book lungs } \\
\hline \text { F. } & \text { King crab } & \text { (vi) } & \text { Body surface } \\
\hline \text { G. } & \text { Prawn } & \text { (vii) } & \text { Moist cuticle } \\
\hline \text { H. } & \text { Labeo } & & \\
\hline
\end{array}
\)
(a)
Which structure of man is similar to spiracle of cockroach?
(a) Spiracle in cockroach and nostril in man are the openings through which air enters the body.
Which of the following options is incorrect about the larynx (sound box)?
(a)Â Larynx is a cartilaginous box containing nine pieces of cartilages.
Which of the following structures close the glottis during swallowing to prevent the entry of food into windpipe?
(b) Epiglottis is a leaf-shaped cartilage that closes the glottis (opening leading into trachea) to check the entry of food into it during swallowing. If during eating, epiglottis remains open, then food particles may enter the trachea (windpipe) leading to reflex action of coughing. This removes the food particles from trachea so that breathing does not get obstructed.
In man and mammals, air passes from outside into the lungs through
Air enters the body through the nose or mouth, which are connected through the nasal and oral cavities to the pharynx.
Air then passes through the larynx (the voice box), and then to the trachea (windpipe). The main bronchial passageways (bronchi) subdivide in the lungs into smaller and smaller airways, called bronchioles and finally to the individual air sacs called alveoli, where oxygen enters the bloodstream. So, the correct answer is ‘Nasal cavity, pharynx, larynx, trachea, bronchi, bronchioles, alveoli’
Study the given figure of respiratory passage carefully and identify the parts labelled as A, B, C, D and E.
\(
\begin{array}{|c|c|c|c|c|c|}
\hline & \text { A } & \text { B } & \text { C } & \text { D } & \mathbf{E} \\
\hline \text { (a) } & \text { Alveolar } & \begin{array}{l}
\text { Secondary } \\
\text { bronchus }
\end{array} & \text { Alveoli } & \text { Bronchioles } & \text { Trachea } \\
\hline \text { (b) } & \text { Alveoli } & \begin{array}{l}
\text { Secondary } \\
\text { bronchus }
\end{array} & \begin{array}{l}
\text { Alveolar } \\
\text { sac }
\end{array} & \text { Trachea } & \text { Bronchioles } \\
\hline \text { (c) } & \begin{array}{l}
\text { Alveolar } \\
\text { sac }
\end{array} & \begin{array}{l}
\text { Tertiary } \\
\text { bronchus }
\end{array} & \text { Alveoli } & \text { Trachea } & \text { Bronchioles } \\
\hline \text { (d) } & \text { Alveoli } & \begin{array}{l}
\text { Tertiary } \\
\text { bronchus }
\end{array} & \begin{array}{l}
\text { Alveolar } \\
\text { sac }
\end{array} & \text { Bronchioles } & \text { Trachea } \\
\hline
\end{array}
\)
(a) In the given figure depicting the respiratory passage in man, the unidentified parts are as follows: (A) Alveolar sac, (B) Secondary bronchus, (C) Alveoli, (D) Bronchioles, and (E) Trachea.
So, the correct answer is ‘
(A) Alveolar sac (B) Secondary bronchus (C)Alveoli (D) Bronchioles
(E)Trachea’.
Mammalian lungs have an enormous number of minute alveoli (air sacs). This is to allow
(a) The number of alveoli in the human lungs has been estimated to be approximately 300 million. This enormous number of alveoli are meant to increase surface area of lungs for diffusion of gases.
The given figure shows the diagrammatic view of human respiratory system. Identify A, B, C and D.
(a) In the given figure depicting the human respiratory system, the unidentified parts are as follows: A-Epiglottis, B-Alveoli, C-Bronchus, D-Diaphragm. So, the correct answer is ‘ A-Epiglottis, B-Alveoli, C- Bronchus, D-Diaphragm’.
The given figures are of human larynx, front view (i) and vertical section (ii).
Identify the labelled parts A to D.
\(
\begin{array}{|l|l|l|l|l|}
\hline & \text { A } & \text { B } & \text { C } & \text { D } \\
\hline \text { (a) } & \text { Glottis } & \text { Larynx } & \text { Vocal cord } & \begin{array}{l}
\text { Cartilaginous rings } \\
\text { of trachea }
\end{array} \\
\hline \text { (b) } & \text { Epiglottis } & \begin{array}{l}
\text { Cartilaginous rings } \\
\text { of trachea }
\end{array} & \text { Trachea } & \text { Thyroid cartilage } \\
\hline \text { (c) } & \text { Glottis } & \begin{array}{l}
\text { Cartilaginous rings } \\
\text { of trachea }
\end{array} & \text { Larynx } & \text { Trachea } \\
\hline \text { (d) } & \text { Epiglottis } & \begin{array}{l}
\text { Bony rings of } \\
\text { trachea }
\end{array} & \begin{array}{l}
\text { Thyroid } \\
\text { cartilage }
\end{array} & \text { Trachea } \\
\hline
\end{array}
\)
(b)
Lungs are enclosed in
(c) The lungs are covered in a membrane called pleural membrane. The outer covering is called parietal pleura and the inner covering is called visceral pleura.
Thoracic chamber is formed dorsally by the (i). ventrally by the (iii), laterally by the (iii) and on lower side by the dome shaped (iv).
Select the correct option to complete the above paragraph.
\(
\begin{array}{|l|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } & \text { (iv) } \\
\hline \text { (a) } & \begin{array}{l}
\text { vertebral } \\
\text { column }
\end{array} & \text { sternum } & \text { ribs } & \text { diaphragm } \\
\hline \text { (b) } & \text { sternum } & \begin{array}{l}
\text { vertebral } \\
\text { column }
\end{array} & \text { diaphragm } & \text { ribs } \\
\hline \text { (c) } & \text { diaphragm } & \text { ribs } & \text { vertebral column } & \text { sternum } \\
\hline \text { (d) } & \text { ribs } & \text { diaphragm } & \begin{array}{l}
\text { vertebral } \\
\text { column }
\end{array} & \text { sternum } \\
\hline
\end{array}
\)
(a)Â
Given below is a list of different steps (i-vi) involved in respiration.
(i) Utilisation of \(\mathrm{O}_2\) by the cells for catabolic reactions.
(ii) Transport of gases by the blood.
(iii) Pulmonary ventilation by which atmospheric air is drawn in and \(\mathrm{CO}_2\) is released out.
(iv) Release of resultant \(\mathrm{CO}_2\).
(v) Diffusion of \(\mathrm{O}_2\) and \(\mathrm{CO}_2\) between blood and tissues.
(vi) Diffusion of gases \(\left(\mathrm{O}_2\right.\) and \(\left.\mathrm{CO}_2\right)\) across alveolar tissues.
Select an option which has correct sequence of all the steps.
(a) Respiration involves the following steps:
(i) Breathing or pulmonary ventilation by which atmospheric air is drawn in and \(\mathrm{CO}_2\) rich alveolar air is released out.
(ii) Diffusion of gases \(\left(\mathrm{O}_2\right.\) and \(\left.\mathrm{CO}_2\right)\) across alveolar membrane.
(iii) Transport of gases by the blood.
(iv) Diffusion of \(\mathrm{O}_2\) and \(\mathrm{CO}_2\) between blood and tissues.
(v) Utilisation of \(\mathrm{O}_2\) by the cells for catabolic reactions and resultant release of \(\mathrm{CO}_2\) (cellular respiration as dealt in the Chapter 12).
Inspiration occurs when there is a negative pressure in the lungs with respect to atmospheric pressure. This negative pressure is achieved when
(a) Because of the pressure gradient between the lungs and the atmosphere, the air moves into and out of the lungs. Inspiration occurs if the pressure within the lungs (intra-pulmonary pressure) is less than the atmospheric pressure i.e. there is a negative pressure in the lungs with respect to atmospheric pressure.
Read the given statements and select the correct option.
Statement 1: Mammals can eat while breathing.
Statement 2: Mammals have negative pressure breathing.
(a) The negative pressure breathing in mammals allows them to eat and breathe at the same time.
Which of the following parts are involved in the mechanism of breathing?
(d)
Fill up the blanks in the following paragraph by selecting the correct option.
The movement of air into and out of the lungs is carried out by creating a (i) between the lungs and the atmosphere. Inspiration can occur if intra-pulmonary pressure is (ii) than the atmospheric pressure. Expiration takes place when the intra-pulmonary pressure is (iii) than the atmospheric pressure. Inspiration is initiated by the (iv) of diaphragm which (v) the volume of thoracic chamber in the antero-posterior axis.
\(
\begin{array}{|l|l|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } & \text { (iv) } & \text { (v) } \\
\hline \text { (a) } & \begin{array}{l}
\text { concentration } \\
\text { gradient }
\end{array} & \text { less } & \text { higher } & \text { relaxation } & \text { increases } \\
\hline \text { (b) } & \begin{array}{l}
\text { concentration } \\
\text { gradient }
\end{array} & \text { higher } & \text { less } & \text { contraction } & \text { decreases } \\
\hline \text { (c) } & \text { pressure gradient } & \text { higher } & \text { less } & \text { relaxation } & \text { decreases } \\
\hline \text { (d) } & \text { pressure gradient } & \text { less } & \text { higher } & \text { contraction } & \text { increases } \\
\hline
\end{array}
\)
(d)
Which of the following sequences is correct to initiate inspiration?
(i) The contraction of external intercostal muscles raises the ribs and sternum
(ii) Volume of thorax increases in the dorso-ventral axis
(iii) Intrapulmonary pressure decreases
(iv) Diaphragm contraction
(v) Air rushes into lungs
(vi) Volume of thorax increases in the anterior-posterior axis
(c) Inspiration can occur if the pressure within the lungs (intra-pulmonary pressure) is less than the atmospheric pressure, i.e., there is a negative pressure in the lungs with respect to atmospheric pressure.
Which of the following changes occur in diaphragm and intercostal muscles when expiration of air takes place?
(c) When the internal intercostal muscles contract and diaphragm relax, the ribs move downward and inward and diaphragm becomes convex (dome-shaped), thus decreasing the volume of thoracic cavity and increasing the pressure inside as compared to the atmospheric pressure outside. This will cause the air to move out (expiration).
During expiration, the diaphragm becomes
(a) When the internal intercostal muscles contract and diaphragm relax, the ribs move .downward and inward and diaphragm becomes convex (dome shaped), thus decreasing the volume of thoracic cavity and increasing the pressure inside as compared to the atmospheric pressure outside. This will cause the air to move out (expiration).
Exhalation is the process of expulsion of air through the respiratory tract. Which figure illustrates the process of exhalation?
(d) When the internal intercostal muscles contract and the diaphragm relax, the ribs move downward and inward and the diaphragm becomes convex\domeshaped, thus decreasing the volume of the thoracic cavity and increasing the pressure inside as compared to the atmospheric pressure outside. This will cause the air to move out (expiration).
The given figure illustrates the changes in lung volume during the process of breathing.
The change from II to III indicates the
(c) The change from II to III indicates decrease in the volume of lungs and thus, increase in the pressure of air inside the lungs. This results in movement of air out of the lungs.
Which of the following statements about the mechanism of ventilation/breathing is incorrect?
(c) Inspiration is an active process while expiration is a passive process. During inspiration the thoracic cage moves upward and forward to increase the volume of thoracic cavity, this contraction is brought about by the activity of the external intercostals, intercondrial intercostals that elevate the ribs, the diaphragm also achieves a dome shape. Here, the contraction of the muscles to pull the ribs and the diaphragm upwards requires energy. Hence, an active process
During expiration the contracted muscles relax, hence a passive process. So, the correct answer is ‘Inspiration is a passive and expiration is an active process.’
Select the correct statement.
(a) Expiration takes place when the intra-pulmonary pressure is higher than the atmospheric pressure. The diaphragm and a specialised set of muscles – external and internal intercostals between the ribs, help in generation of such gradients. Inspiration is initiated by the contraction of diaphragm which increases the volume of thoracic chamber in the antero-posterior axis.
A person breathing normally at rest, takes in and expels approximately half a litre of air during each respiratory cycle. This is called
(b) The volume of air inspired or expired during normal breath is called tidal volume. It is about \(500 \mathrm{~mL}\) of air in average young adult man.
Which one of the following statements is incorrect?
(d) In insects, blood (haemolymph) does not contain an oxygen-carrying pigment. Hence it does not help in respiration. Instead, insects have spiracles and tracheae that carry \(\mathrm{O}_2\) to different tissues.
Given below are four respiratory capacities and their respiratory volumes.
\(
\begin{array}{|c|l|c|}
\hline & \begin{array}{c}
\text { Respiratory volumes and } \\
\text { capacities }
\end{array} & \text { Volume of air } \\
\hline \text { (i) } & \text { Tidal volume } & 500 \mathrm{~mL} \\
\hline \text { (ii) } & \text { Vital capacity } & 2500 \mathrm{~mL} \\
\hline \text { (iii) } & \text { Functional residual capacity } & 2300 \mathrm{~mL} \\
\hline \text { (iv) } & \text { Total lung capacity } & 3200 \mathrm{~mL} \\
\hline
\end{array}
\)
Select the correct matched pair.
(c)
\(
\begin{aligned}
&\text { The correct matching of respiratory capacities with their respiratory volumes are: }\\
&\begin{array}{|l|l|}
\hline \text { Respiratory Capacities } & \text { Resiratory Volumes } \\
\hline \text { Residual volume } & 1200 \mathrm{~mL} \\
\hline \text { Vital capacity } & 4500 \mathrm{~mL} \\
\hline \text { Inspiratory reserve volume } & 2500 \mathrm{~mL} \\
\hline \text { Inspiratory capacity } & 3500 \mathrm{~mL} \\
\hline
\end{array}
\end{aligned}
\)
Complete the following sentences by selecting the correct option.
(A) Inspiratory capacity (IC) = (i) + IRV
(B) (ii) \(=T V+I R V+E R V\)
(C) Functional residual capacity (FRC) \(=E R V+\) (iii)
\(
\begin{array}{|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } \\
\hline \text { (a) } & \text { Vital capacity } & \text { Tidal volume } & \text { Residual volume } \\
\hline \text { (b) } & \text { Expiratory capacity } & \text { Residual volume } & \begin{array}{l}
\text { Inspiratory reserve } \\
\text { volume }
\end{array} \\
\hline \text { (c) } & \text { Tidal volume } & \text { Vital capacity } & \text { Residual volume } \\
\hline \text { (d) } & \text { Tidal volume } & \text { Total lung capacity } & \text { Expiratory capacity } \\
\hline
\end{array}
\)
(c)Â
Consider the following statements each with one or two blanks.
(i) Left lung has (1) lobes and right lung has (2) lobes.
(ii) Prawn respires with (3) and insects with (4).
(iii) Amount of air inhaled and exhaled with maximum effort is referred to as the (5) of the lungs. Fill up the above blanks by selecting the correct option.
Fill up the above blanks by selecting the correct option.
(b) Prawn respires with gills (Branchial respiration) and insects respire by tracheae (Tracheal respiration).
Consider the following statements each with two blanks.
(i) Actually, only about (1) \(\mathrm{mL}\) of air enters the lung alveoli for the exchange of gases. The remaining fills the respiratory passage and is termed (2).
(ii) The amount of air which one can inhalewith maximum effort and also exhale with maximum effort is termed as (3). It is about (4) in normal adult person.
(iii) During normal quiet breathing, on an average, approximately (5) \(\mathrm{mL}\) of air is inspired or expired by adult human male in each breath. It is termed as (6) volume.
Which of the following options gives the correct fill-ups for the respective blank numbers from (1) to (6) in the above statements?
(a)Â Actually, only about \(350 \mathrm{~mL}\) of air (out of total \(500 \mathrm{~mL}\) tidal volume) enters the lung alveoli for the exchange of gases. The remaining \(150 \mathrm{~mL}\) fills the respiratory passage and is termed as dead air space because no exchange of gases takes place here.
The inspiratory capacity includes
(b) Inspiratory Capacity (IC): Total volume of air a person can inspire after a normal expiration. This includes tidal volume and inspiratory
reserve volume ( TV+IRV).
Vital capacity of lungs is
(d) Vital capacity is the maximum volume of air a person can breathe in after a forced expiration or the maximum volume of air a person can breathe out after a forced inspiration. This equals the inspiratory reserve volume (IRV) + expiratory reserve volume (ERV) + tidal volume (TV). Its value is \(3400 \mathrm{~mL}-4800 \mathrm{~mL}\).
After forceful inspiration, the amount of air that can be breathed out by maximum forced expiration is equal to
(c) Vital capacity is the maximum volume of air a person can breathe in after a forced expiration or the maximum volume of air a person can breathe out after a forced inspiration. This equals the inspiratory reserve volume (IRV) + expiratory reserve volume (ERV) + tidal volume (TV). Its value is \(3400 \mathrm{~mL}-4800 \mathrm{~mL}\).
Match column I with column II and select the correct option from the given codes.
\(
\begin{array}{|l|l|l|l|}
\hline & \text { Column I } & & \text { Column II } \\
\hline \text { A. } & \text { Tidal volume } & \text { (i) } & 2500-3000 \mathrm{~mL} \text { of air } \\
\hline \text { B. } & \text { Inspiratory reserve volume } & \text { (ii) } & 1000 \mathrm{~mL} \text { of air } \\
\hline \text { C. } & \text { Expiratory reserve volume } & \text { (iii) } & 500 \mathrm{~mL} \text { of air } \\
\hline \text { D. } & \text { Residual volume } & \text { (iv) } & 3400-4800 \mathrm{~mL} \text { of air } \\
\hline \text { E. } & \text { Vital capacity } & \text { (v) } & 1200 \mathrm{~mL} \text { of air } \\
\hline
\end{array}
\)
(b)
Match column I with column II and select the correct option from the codes given below.
\(
\begin{array}{|l|l|l|l|}
\hline & \text { Column I } & & \text { Column II } \\
\hline \text { A. } & \text { TV + ERV } & \text { (i) } & \text { Expiratory capacity } \\
\hline \text { B. } & \text { RV + ERV + TV + IRV } & \text { (ii) } & \text { Total lung capacity } \\
\hline \text { C. } & \text { ERV + RV } & \text { (iii) } & \begin{array}{l}
\text { Functional residual } \\
\text { capacity }
\end{array} \\
\hline
\end{array}
\)
(a)
The exchange of gases in the alveoli of the lungs takes place by
(d) The exchange of gases in the alveoli of the lungs takes place by simple diffusion. The exchange of gases between the alveoli and blood in the lungs is the result of difference in partial pressure of respiratory gases.
The given figure shows diagrammatic representation of exchange of gases at the alveolus and the body tissues with blood and transport of oxygen and carbon dioxide. Identify the blood vessels A to D.
In the given figure depicting the exchange of gases at the alveolus and the body tissues with blood and transport of oxygen and carbon dioxide. The unidentified parts in the given diagram are as follows: A-Systemic vein, B-Pulmonary artery, C- Pulmonary vein, and D- Systemic artery. So, the correct answer is option (a).
Consider the following statements each with two blanks.
(i) Diaphragm contracts to help in (1) while the contraction of abdominal muscles help in (2).
(ii) Vital capacity of trained athletes is (3) than that of non-athletes while the vital capacity of non-smokers is (4) than that of smokers.
(iii) Alveolar \(\mathrm{pO}_2\) is (5) than the venous \(\mathrm{pO}_2\) while arterial \(\mathrm{pO}_2\) is (6) than the alveolar \(\mathrm{pO}_2\).
Which of the following options gives the correct fill-ups for the respective blanks numbered from (1) to (6) in the above statements?
(c)
Which of the following would have the same \(\mathrm{O}_2\) content?
(b) Blood entering the right side of the heart i.e., right atrium is a deoxygenated blood having partial pressure of \(40 \mathrm{~mm}\) \(\mathrm{Hg}\). Blood leaving the right side of the heart i.e., right ventricle will also have almost same partial pressure as the blood is moving from right atrium to right ventricle and also no exchange of gases occurs in this path.
What is the approximate normal composition of alveolar air?
(a)
The \(\mathrm{CO}_2\) content by volume, in the atmospheric air is about
(c)
Among the following the partial pressure of oxygen is maximum in
(d) The partial pressure of \(\mathrm{O}_2\) in expired air is 116 \(\mathrm{mm} \mathrm{Hg}\). In alveolar air it is \(104 \mathrm{~mm} \mathrm{Hg}\), in arterial blood it is \(95 \mathrm{~mm} \mathrm{Hg}\) and in venous blood it is \(40 \mathrm{~mm} \mathrm{Hg}\).
In lungs, the air is separated from the venous blood through
(b) The wall of the alveoli is very thin and has a rich network of blood capillaries. The alveolar capillary membrane consists mainly of squamous epithelium, epithelial basement membrane, a thin interstitial space, capillary basement membrane and capillary endothelium.
The factor which does not affect the rate of alveolar diffusion is
(d) Solubility of the gases as well as the thickness of the membranes involved in diffusion are also some important factors that can affect the
rate of diffusion.
Which of the following statements is correct?
(c) The thoracic cavity is anatomically an air tight chamber as it consists of lungs that further consist of air sacs in which the air remains trapped. The contraction of the external intercostal muscles lifts up the ribs and sternum. RBCs transport both \(\mathrm{O}_2\) and \(\mathrm{CO}_2\). Healthy man can inspire or expire 6000 to \(8000 \mathrm{~mL}\) of air per minute.
After taking a long deep breath we do not respire for some seconds due to
(c)Â
A large proportion of oxygen remains unused in the human blood even after its uptake by the body tissues. This \(\mathrm{O}_2\)
(a)
Which of the following is true for \(\mathrm{CO}_2\) concentration?
(a) Concentration or partial pressure of \(\mathrm{CO}_2\left(\mathrm{pCO}_2\right)\) is 40 \(\mathrm{mm} \mathrm{Hg}\) in alveolar air and \(32 \mathrm{~mm} \mathrm{Hg}\) in expired air.
During rest, the metabolic needs of the body are at their minimum. Which of the following is indicative of this situation?
(d) Metabolic activities are the sum of physical and chemical processes taking place in the living organisms. Rate of breathing, \(\mathrm{O}_2\) intake and \(\mathrm{CO}_2\) output and pulse rate slow down indicating that the metabolic needs of the body are at their minimum during rest.
Consider the following four statements ( i – iv) and select the correct option stating which ones are true (T) and which ones are false (F).
(i) Formation of oxyhaemoglobin occurs on alveolar surface.
(ii) During gaseous exchange the gases diffuse from high partial pressure to low partial pressure.
(iii) Carbon dioxide cannot be transported with haemoglobin.
(iv) Earthworm respires through parapodia.
\(
\begin{array}{|l|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } & \text { (iv) } \\
\hline \text { (a) } & \text { T } & \text { F } & \text { T } & \text { F } \\
\hline \text { (b) } & \text { F } & \text { F } & \text { T } & \text { F } \\
\hline \text { (c) } & \text { F } & \text { T } & \text { F } & \text { T } \\
\hline \text { (d) } & \text { T } & \text { T } & \text { F } & \text { F } \\
\hline
\end{array}
\)
(d) About \(20-25 \% \mathrm{CO}_2\) is carried by haemoglobin as carbaminohaemoglobin. Earthworm respires through body wall.
Besides RBC, blood plasma also carries \(\mathrm{O}_2\) in solution. The percentage is
(d) About \(3 \%\) of oxygen in blood is dissolved in the plasma which carries oxygen to the body cells.
Which of the following statements is true about RBCs in humans?
(a) Nearly \(20-25 \%\) of \(\mathrm{CO}_2\) is transported by RBCs whereas \(70 \%\) of it is carried as bicarbonate. About \(7 \%\) of \(\mathrm{CO}_2\) is carried in a dissolved state through plasma. About \(97 \%\) of \(\mathrm{O}_2\) is carried by RBCs in the blood. About \(3 \%\) of \(\mathrm{O}_2\) is transported in a dissolved state through the plasma.
The carbon dioxide is transported via blood to lungs mostly
(c) Nearly \(20-25 \%\) of \(\mathrm{CO}_2\) is transported by RBCs whereas \(70 \%\) of it is carried as bicarbonate. About \(7 \%\) of \(\mathrm{CO}_2\) is carried in a dissolved state through plasma. About \(97 \%\) of \(\mathrm{O}_2\) is carried by RBCs in the blood. About \(3 \%\) of \(\mathrm{O}_2\) is transported in a dissolved state through the plasma.
Blood carries the \(\mathrm{CO}_2\) in three forms. The correct percentages of \(\mathrm{CO}_2\) in these forms are
\(
\begin{array}{|l|l|l|l|}
\hline & \begin{array}{l}
\text { As carbamino- } \\
\text { haemoglobin in RBC }
\end{array} & \begin{array}{l}
\text { As } \\
\text { bicarbonates }
\end{array} & \begin{array}{l}
\text { Dissolved form in } \\
\text { plasma }
\end{array} \\
\hline \text { (a) } & 20-25 \% & 70 \% & 7 \% \\
\hline \text { (b) } & 70 \% & 20-25 \% & 7 \% \\
\hline \text { (c) } & 20-25 \% & 7 \% & 70 \% \\
\hline \text { (d) } & 7 \% & 20-25 \% & 70 \% \\
\hline
\end{array}
\)
(a) Nearly \(20-25 \%\) of \(\mathrm{CO}_2\) is transported by RBCs whereas \(70 \%\) of it is carried as bicarbonate. About \(7 \%\) of \(\mathrm{CO}_2\) is carried in a dissolved state through plasma. About \(97 \%\) of \(\mathrm{O}_2\) is carried by RBCs in the blood. About \(3 \%\) of \(\mathrm{O}_2\) is transported in a dissolved state through the plasma.
Bulk of oxygen diffuses from the plasma into the red blood corpuscles where it joins loosely with \(\mathrm{Fe}^{2+}\) ions of haemoglobin \((\mathrm{Hb})\) to form bright red oxyhaemoglobin \(\left(\mathrm{HbO}_2\right)\). This process is called
(c) The process of addition of oxygen to an atom or a molecule in order to increase the concentration of oxygen in tissue is generally referred to as oxygenation. When the bulk of oxygen diffuses from the plasma into the red blood corpuscles where it joins loosely with \(\mathrm{Fe} 2+\) ions of haemoglobin \((\mathrm{Hb})\) to form bright red oxyhaemoglobin ( \(\mathrm{HbO} 2\) ) it is also an example of oxygenation.
So the correct answeris ‘oxvgenation’
How many molecules of \(\mathrm{O}_2\) does one haemoglobin carries?
(a) Hb contains a protein portion called globin and a pigment portion called haem. The haem portion consists of four atoms of iron, each capable of combining with a molecule of \(\mathrm{O}_2\). Thus, one \(\mathrm{Hb}\) carries 4 molecules of \(\mathrm{O}_2\).
The oxygen dissociation curve is
(c)Â The oxygen dissociation curve is sigmoid curve i.e. S-shaped.
Which of the following is incorrect about the given graph?
(c)Â The part ‘ B ‘ in the graph represents partial pressure of oxygen.
The given graph shows an oxygen dissociation curve for haemoglobin.
Where in the body will haemoglobin be saturated at the percentages shown at points 1,2 and 3 on the graph?
\(
\begin{array}{lccc}
& \text { Left ventricle } & \text { Pulmonary vein } & \text { Vena cava } \\
\text { (a) } & 1 & 2 & 3 \\
\text { (b) } & 2 & 1 & 3 \\
\text { (c) } & 2 & 3 & 1 \\
\text { (d) } & 3 & 2 & 1
\end{array}
\)
(c) The relationship between the partial pressure of \(\mathrm{O}_2\left(\mathrm{pO}_2\right)\) and percentage saturation of the \(\mathrm{Hb}\) with \(\mathrm{O}_2\) is graphically illustrated by a curve called oxygen dissociation curve. The haemoglobin is most saturated with oxygen in the pulmonary vein, as this vein is carrying oxygenated blood from the lungs towards the left auricle of the heart. From the left auricle the blood moves to the left ventricle where saturation of \(\mathrm{Hb}\) with \(\mathrm{O}_2\) slightly reduces. Vena cava carries deoxygenated blood from all the organs of the body towards right auricle, thus, \(\mathrm{Hb}\) is less saturated with \(\mathrm{O}_2\).
When temperature decreases, oxy-Hb curve becomes
(a) When temperature decreases, oxy-Hb curve will become more steep. The steep rise of the curve indicates high affinity of \(\mathrm{Hb}\) for \(\mathrm{O}_2\).
Which of the following factors is not favourable for the formation of oxyhaemoglobin?
\(
\text { (d) Low } \mathrm{pCO}_2 \text { favours the formation of oxyhaemoglobin. }
\)
63Consider the following four statements and select the correct option stating which ones are true (T) and which ones are false (F).
(i) Expiration is normally brought about by the relaxation of inspiratory muscles.
(ii) Oxyhaemoglobin can hold much less carbon dioxide in the form of carbaminohaemoglobin than what deoxyhaemoglobin can.
(iii) A person can expel all the air from the lungs by a forceful expiration.
(iv) A rise in \(\mathrm{PCO}_2\) increases the oxygen-affinity of haemoglobin.
\(
\begin{array}{|l|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } & \text { (iv) } \\
\hline \text { (a) } & \text { F } & \text { F } & \text { T } & \text { T } \\
\hline \text { (b) } & \text { T } & \text { F } & \text { T } & \text { T } \\
\hline \text { (c) } & \text { T } & \text { T } & \text { F } & \text { F } \\
\hline \text { (d) } & \text { F } & \text { F } & \text { F } & \text { T } \\
\hline
\end{array}
\)
(b) A person cannot expel all the air from the lungs even after forceful expiration. The volume of air which remains in the lungs after the most forceful expiration is called residual volume. It is about \(1100 \mathrm{~mL}\) to \(1200 \mathrm{~mL}\). A rise in \(\mathrm{pCO}_2\) decreases the \(\mathrm{O}_2\) affinity of haemoglobin.
In the tissues, high concentrations of carbon dioxide
(c) : Increase in the \(\mathrm{CO}_2\) content of the blood decreases the \(\mathrm{pH}\) of the blood. This decreases the affinity of \(\mathrm{O}_2\) with \(\mathrm{Hb}\). This is called Bohr effect and is closely related to the fact that deoxygenated \(\mathrm{Hb}\) binds hydrogen ions more actively than does the \(\mathrm{Hb}\). This facilitates gaseous exchange because more \(\mathrm{O}_2\) is released in the tissues where the amount of \(\mathrm{CO}_2\) is more due to metabolic activity. At the same time, more \(\mathrm{O}_2\) is taken up by the lungs or gills when the amount of \(\mathrm{CO}_2\) is low.
Fetal haemoglobin has \(X\) affinity for oxygen than that of mother’s haemoglobin during gestation. \(X\) is
(b) Functionally, fetal haemoglobin has a higher affinity to bind with oxygen molecules than the adult (or maternal) haemoglobin, giving the developing fetus better access to oxygen from the mother’s blood stream.
Read the given statements and select the correct option.
Statement 1: About \(70 \%\) of \(\mathrm{CO}_2\) that enters RBCs changes into \(\mathrm{HCO}_3^{-}\)for transport in plasma to the lungs where it reconverts into \(\mathrm{CO}_2\) for elimination.
Statement 2: About \(40 \%\) of \(\mathrm{CO}_2\) that enters RBCs changes into carbaminohaemoglobin which releases \(\mathrm{O}_2\) in the lungs.
(b) About \(20-25 \%\) of \(\mathrm{CO}_2\) is carried by \(\mathrm{Hb}\) as carbaminohaemoglobin. \(\mathrm{CO}_2\) reacts directly with amine radicals \(\left(\mathrm{NH}_2\right)\) of \(\mathrm{Hb}\) to form an unstable compound called carbaminohaemoglobin which releases \(\mathrm{CO}_2\) in the lungs.
Match column I with column II and select the correct option from the codes given below.
\(
\begin{array}{|c|l|c|l|}
\hline & \text { Column I } & & \text { Column II } \\
\hline \text { A. } & \text { Tracheoles } & \text { (i) } & \text { Yeast } \\
\hline \text { B. } & \text { Carbonic anhydrase } & \text { (ii) } & \text { Fish } \\
\hline \text { C. } & \text { Lactic acid } & \text { (iii) } & \text { Inspiration } \\
\hline \text { D. } & \text { Fermentation } & \text { (iv) } & \text { Vital capacity } \\
\hline \text { E. } & \text { Gill filaments } & \text { (v) } & \text { Fast muscle } \\
\hline \text { F. } & \text { Cutaneous respiration } & \text { (vi) } & \text { Insect } \\
\hline \text { G. } & \text { Diaphragm } & \text { (vii) } & \text { Bicarbonates } \\
\hline & & \text { (viii) } & \text { Earthworm } \\
\hline
\end{array}
\)
(a)
The enzyme that increases the reaction rate between \(\mathrm{CO}_2\) and \(\mathrm{H}_2 \mathrm{O}\) in red blood cells is
(a) About \(70 \%\) of \(\mathrm{CO}_2\) is transported in plasma in the form of bicarbonates. \(\mathrm{CO}_2\) diffuses into \(\mathrm{RBC}\), combines with water and forms carbonic acid. Carbonic acid being unstable quickly dissociates into bicarbonate ions and hydrogen ions. This reaction is thousand times faster in RBCs as compared to plasma, as RBCs contain carbonic anhydrase enzyme that reversibly catalyses the conversion of \(\mathrm{CO}_2\) and water to carbonic acid.
Which of the following equations is correct?
(b) About \(70 \%\) of \(\mathrm{CO}_2\) is transported in plasma in the form of bicarbonates. \(\mathrm{CO}_2\) diffuses into \(\mathrm{RBC}\), combines with water and forms carbonic acid. Carbonic acid being unstable quickly dissociates into bicarbonate ions and hydrogen ions. This reaction is thousand times faster in RBCs as compared to plasma, as RBCs contain carbonic anhydrase enzyme that reversibly catalyses the conversion of \(\mathrm{CO}_2\) and water to carbonic acid.
People living at sea level have around 5 million RBC per cubic millimetre of their blood whereas those living at an altitude of 5400 metres have around 8 million. This is because at high altitude
(c) Number of RBCs per cubic millimetre of blood is likely to be higher in people living at high altitudes. This is in response to the air being less dense at high altitude and thus more RBCs (and hence more \(\mathrm{Hb}\) ) are needed to absorb the required amount of \(\mathrm{O}_2\) from the air having low \(\mathrm{PO}_2\).
Identify the correct statement with reference to transport of respiratory gases by blood.
(b)
In humans, which of the following is not a step in respiration?
(d) Respiration involves the following steps:
(i) Breathing or pulmonary ventilation by which atmospheric air is drawn in and \(\mathrm{CO}_2\) rich alveolar air is released out.
(ii) Diffusion of gases \(\left(\mathrm{O}_2\right.\) and \(\left.\mathrm{CO}_2\right)\) across alveolar membrane.
(iii) Transport of gases by the blood.
(iv) Diffusion of \(\mathrm{O}_2\) and \(\mathrm{CO}_2\) between blood and tissues.
(v) Utilisation of \(\mathrm{O}_2\) by the cells for catabolic reactions and resultant release of \(\mathrm{CO}_2\) (cellular respiration as dealt in the Chapter 12).
Although much \(\mathrm{CO}_2\) is carried in blood, yet blood does not become acidic, because
(c) Although much \(\mathrm{CO}_2\) is carried in the blood, yet blood does not become acidic. It is due to \(\mathrm{CO}_2\) transport and buffering action of blood. The main buffer present in the blood is bicarbonate (which is formed during \(\mathrm{CO}_2\) transport in the blood). Bicarbonates exist in equilibrium with carbonic acid which in turn can be converted to \(\mathrm{CO}_2\) and water.
\(
\mathrm{H}_2 \mathrm{O}+\mathrm{CO}_2 \rightleftharpoons \mathrm{H}_2 \mathrm{CO}_3 \rightleftharpoons \mathrm{H}^{+}+\mathrm{HCO}_3^{-}
\)
Which one of the following can bind several hundred times more strongly to the haemoglobin than oxygen?
(c)
Select the correct statement.
(b) \(\mathrm{CO}_2\) is carried by haemoglobin as carbamino-haemoglobin (about 20-25 per cent). This binding is related to the partial pressure of \(\mathrm{CO}_2\). \(\mathrm{pO}_2\) is a major factor which could affect this binding. When \(\mathrm{pCO}_2\) is high and \(\mathrm{pO}_2\) is low as in the tissues, more binding of carbon dioxide occurs whereas, when the \(\mathrm{pCO}_2\) is low and \(\mathrm{pO}_2\) is high as in the alveoli, dissociation of \(\mathrm{CO}_2\) from carbamino-haemoglobin takes place, i.e., \(\mathrm{CO}_2\) which is bound to haemoglobin from the tissues is delivered at the alveoli.Â
Match column I with column II and select the correct option from the given codes.
\(
\begin{array}{|c|c|c|c|}
\hline & \text { Column I } & & \text { Column II } \\
\hline \text { A. } & \text { Trachea } & \text { (i) } & \mathrm{pO}_2 \text { in alveolar air } \\
\hline \text { B. } & \text { Respiratory centre } & \text { (ii) } & \text { ATP } \\
\hline \text { C. } & \text { Yeast } & \text { (iii) } & \text { Cartilaginous rings } \\
\hline \text { D. } & \text { Pigeon } & \text { (iv) } & \text { Medulla oblongata } \\
\hline \text { E. } & \text { Fish } & \text { (v) } & \text { Larynx } \\
\hline \text { F. } & \begin{array}{l}
\text { Biologically useful } \\
\text { energy }
\end{array} & \text { (vi) } & \text { Lungs } \\
\hline \text { G. } & 100 \mathrm{~mm} \mathrm{Hg} & \text { (vii) } & \text { Ethanol } \\
\hline \mathrm{H} \text {. } & \text { Vocal cords } & \text { (viii) } & \text { Branchial respiration } \\
\hline
\end{array}
\)
(a)
Pneumotaxic centre which can moderate the functions of the respiratory rhythm centre is present in
(a)Â Pneumotaxic centre is present in the dorsal part of the pons varolii of the brain. Its function is primarily to limit inspiration.
Match column I with column II and select the correct option from the codes given below.
\(
\begin{array}{|l|l|c|l|}
\hline & \text { Column I } & & \text { Column II } \\
\hline \text { A. } & \begin{array}{l}
\text { Carbamino- } \\
\text { haemoglobin }
\end{array} & \text { (i) } & \text { Inspiration } \\
\hline \text { B. } & \text { Diaphragm } & \text { (ii) } & \text { Hamburger’s phenomenon } \\
\hline \text { C. } & \text { Larynx } & \text { (iii) } & \text { Diffusion of } \mathrm{Cl}^{-} \text {into } \mathrm{RBCs} \\
\hline \text { D. } & \text { Pons varolii } & \text { (iv) } & \text { Carbon dioxide } \\
\hline \text { E. } & \text { Chloride shift } & \text { (v) } & \text { Cartilages } \\
\hline & & \text { (vi) } & \text { Pneumotaxic centre } \\
\hline & & \text { (vii) } & \text { Expiration } \\
\hline
\end{array}
\)
(a)
Chemosensitive area of respiratory centre in medulla is affected by
(c) A chemosensitive area situated adjacent to the rhythm centre of the medulla is highly sensitive to changes in \(\mathrm{CO}_2\) and hydrogen ion concentrations in blood. Increase in \(\mathrm{CO}_2\) and \(\mathrm{H}^{+}\)ions stimulate this centre, which in turn stimulate the rhythm centre to make necessary adjustments in the respiratory process by which these substances can be eliminated.
Fill up the blanks in the following paragraph by selecting the correct option.
Human beings have a significant ability to maintain and moderate the respiratory rhythm to suit the demands of the body tissues. This is done by the neural system. A specialised centre present in the medulla region of the brain called (i) is primarily responsible for this regulation. Another centre present in the pons region of the brain called (ii) can moderate the functions of the respiratory rhythm centre. Neural signal from this centre can reduce the duration of (iii) and thereby alter the respiratory rate. A (iv) is situated adjacent to the rhythm centre which is highly sensitive to \(\mathrm{CO}_2\) and hydrogen ions.
\(
\begin{array}{|l|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } & \text { (iv) } \\
\hline \text { (a) } & \begin{array}{l}
\text { Chemosensitive } \\
\text { area }
\end{array} & \begin{array}{l}
\text { Respiratory } \\
\text { rhythm centre }
\end{array} & \text { Expiration } & \begin{array}{l}
\text { Pneumotaxic } \\
\text { centre }
\end{array} \\
\hline \text { (b) } & \begin{array}{l}
\text { Respiratory } \\
\text { rhythm centre }
\end{array} & \begin{array}{l}
\text { Pneumotaxic } \\
\text { Centre }
\end{array} & \text { Inspiration } & \begin{array}{l}
\text { Chemosensitive } \\
\text { area }
\end{array} \\
\hline \text { (c) } & \begin{array}{l}
\text { Respiratory } \\
\text { rhythm centre }
\end{array} & \begin{array}{l}
\text { Chemosensitive } \\
\text { area }
\end{array} & \text { Expiration } & \begin{array}{l}
\text { Pneumotaxic } \\
\text { centre }
\end{array} \\
\hline \text { (d) } & \begin{array}{l}
\text { Pneumotaxic } \\
\text { centre }
\end{array} & \begin{array}{l}
\text { Chemosensitive } \\
\text { area }
\end{array} & \text { Inspiration } & \begin{array}{l}
\text { Respiratory } \\
\text { rhythm centre }
\end{array} \\
\hline
\end{array}
\)
(b)
Rate of breathing is controlled mainly by
(a) Rate of breathing is mainly controlled by \(\mathrm{CO}_2\) level in the blood. Excess \(\mathrm{CO}_2\) mainly stimulate the respiratory centre of the brain and increase the inspiratory and expiratory signals to the respiratory muscles.
The respiratory centre in the brain is stimulated by
(c) Rate of breathing is mainly controlled by \(\mathrm{CO}_2\) level in the blood. Excess \(\mathrm{CO}_2\) mainly stimulate the respiratory centre of the brain and increase the inspiratory and expiratory signals to the respiratory muscles.
Complete the following sentence by selecting the correct option.
Receptors associated with the aortic arch and carotid artery can recognise changes in (i) and (ii) concentration and send necessary signals to (iii) for remedial actions.
\(
\begin{array}{|l|l|l|l|}
\hline & \text { (i) } & \text { (ii) } & \text { (iii) } \\
\hline \text { (a) } & \mathrm{O}_2 & \mathrm{CO}_2 & \text { pneumotaxic centre } \\
\hline \text { (b) } & \mathrm{CO}_2 & \mathrm{H}^{+} & \text {rhythm centre } \\
\hline \text { (c) } & \mathrm{CO}_2 & \mathrm{H}^{+} & \text {apneustic centre } \\
\hline \text { (d) } & \mathrm{O}_2 & \mathrm{H}^{+} & \text {pneumotaxic centre } \\
\hline
\end{array}
\)
(b) Receptors associated with aortic arch and carotid artery can recognise change in \(\mathrm{CO}_2\) and \(\mathrm{H}^{+}\)concentration and send necessary signals to rhythm centre for remedial actions.
Complete the following sentence by selecting the correct option.
The breathing rhythm is generated in the (i) and is influenced by variation in levels of (ii) in the blood.
\(
\begin{array}{|l|l|l|}
\hline & \text { (i) } & \text { (ii) } \\
\hline \text { (a) } & \text { medulla } & \mathrm{CO}_2 \\
\hline \text { (b) } & \text { medulla } & \mathrm{O}_2 \\
\hline \text { (c) } & \text { frontal lobe } & \mathrm{CO}_2 \text { and } \mathrm{O}_2 \\
\hline \text { (d) } & \text { frontal lobe } & \mathrm{CO}_2 \\
\hline
\end{array}
\)
(a) The basic rhythm of respiration is generated mainly in the dorsal respiratory group in the medulla. Changes in blood carbon dioxide is believed to stimulate the neurons in chemosensitive area which affect the rhythm centre. \(\mathrm{CO}_2\) acts by forming carbonic acid which dissociates into \(\mathrm{H}^{+}\)and \(\mathrm{HCO}_3^{-}\). \(\mathrm{H}^{+}\)has direct effect on this. Oxygen does not have a significant direct effect on rhythm centre.
When \(\mathrm{CO}_2\) concentration in blood increases breathing becomes
(d)Â When \(\mathrm{CO}_2\) concentration in blood increases, breathing becomes faster and deeper. The effect of rising \(\mathrm{CO}_2\) concentration is due to decrease in affinity of \(\mathrm{Hb}\) for \(\mathrm{O}_2\). Thus, the \(\mathrm{CO}_2\) released in the tissues accelerates the delivery of \(\mathrm{O}_2\) (called Bohr effect), due to which breathing becomes faster and deeper.
Read the given statements and select the correct option.
Statement 1: Rate of breathing is regulated by respiratory centres present in the medulla oblongata.
Statement 2: Changes in the \(\mathrm{CO}_2\) level of the arterial blood control the rate of breathing.
(a) Rate of breathing is mainly controlled by \(\mathrm{CO}_2\) level in the blood. Excess \(\mathrm{CO}_2\) mainly stimulate the respiratory centre of the brain and increase the inspiratory and expiratory signals to the respiratory muscles.
Read the following four statements (i) – (iv) with certain mistakes in two of them.
(i) A water breather expends much more energy in ventilating its respiratory surface than an airbreathing one.
(ii) Lungs become empty after forceful expiration.
(iii) The exchange of gases in the lungs is interrupted during expiration.
(iv) Respiratory movements are controlled by \(\mathrm{CO}_2\) concentration of arterial blood.
Which of the above two statements have mistakes?
(b) Expiration takes place when the intra-pulmonary pressure is higher than the atmospheric pressure. The diaphragm and a specialised set of muscles – external and internal intercostals between the ribs, help in generation of such gradients. Inspiration is initiated by the contraction of diaphragm which increases the volume of thoracic chamber in the antero-posterior axis.
The urge to inhale in humans results from
(a) Rate of breathing is mainly controlled by \(\mathrm{CO}_2\) level in the blood. Excess \(\mathrm{CO}_2\) mainly stimulate the respiratory centre of the brain and increase the inspiratory and expiratory signals to the respiratory muscles.
Read the following four statements carefully.
(i) Ventral respiratory group of neurons of medulla oblongata can cause both inspiration and expiration.
(ii) The part of the respiratory system starting with the external nostrils up to the terminal bronchioles constitutes the respiratory or exchange part of the respiratory system.
(iii) During swallowing epiglottis can be covered by a thin elastic cartilaginous flap called glottis to prevent the entry of food into the larynx.
(iv) Binding of oxygen with haemoglobin is primarily related to partial pressure of \(\mathrm{O}_2\).
Which of the above two statements are correct?
(d) The part of the respiratory system starting with the external nostrils up to the terminal bronchioles constitutes the conducting part whereas the alveoli and their ducts form the respiratory or exchange part. During swallowing, glottis can be covered by a thin elastic cartilaginous flap called epiglottis to prevent the entry of food into the larynx.
Emphysema is a condition resulting from
(a) Emphysema is a respiratory disorder which causes the inflation or abnormal distension of the bronchioles or alveolar sacs resulting in the loss of their elasticity. It is caused by cigarette smoking and chronic bronchitis.
Which one of the following is the incorrect statement for respiration in humans?
(d) Most of the Carbon dioxide is carried in the form of bicarbonate ions. Grinding or stone breaking industries produce so much dust that long exposure to this can give rise to inflammation of lungs leading to fibrosis (proliferation of fibrous tissues) and thus causing serious lung damage. Inflammation of the bronchi may also be caused by cigarette smoking. The primary function of pneumotaxic centre is to limit inspiration which increases breathing rate.
Name the pulmonary disease in which alveolar surface area involved in gas exchange is drastically reduced due to damage in the alveolar walls.
94. (d) : Emphysema is an inflation or abnormal distension of the bronchioles or alveolar sacs of the lungs. Many of the septa between the alveoli are destroyed and much of the elastic tissue of the lungs is replaced by connective tissue. As the alveolar septa collapse, the surface area for gas exchange is greatly reduced. There is a loss of elasticity in the walls of bronchioles or alveolar sacs. As a result, the alveolar sacs remain filled with air even after expiration. The exhalation becomes more difficult. The lungs remain inflated. Major causes of emphysema are cigarette smoking and the inhalation of smoke or other toxic substances over a period of time.
Visiting high mountains may cause altitude sickness in men living in plain areas. Prime cause of this is
(c) The effects of high altitude on humans are considerable. The percentage oxygen saturation of haemoglobin determines the content of oxygen in the blood. When a person living in the plain area visit high mountains up to around 2,100 \(\mathrm{m}\) ( 7,000 feet) above sea level, the saturation of oxyhaemoglobin begins to decrease rapidly in the blood and can cause hypoxia. So, the correct answer is “Decreased partial pressure of oxygen”.
Carbon monoxide can kill a person because of it’s extremely high affinity for
(a) Carbon monoxide combines with \(\mathrm{Hb}\) far more readily than \(\mathrm{O}_2\) ( \(\mathrm{CO}\) has about 200 times greater affinity for \(\mathrm{Hb}\) as compared to \(\mathrm{O}_2\) ), forming a relatively stable compound carboxyhaemoglobin. This causes low supply of \(\mathrm{O}_2\) to the body cells leading to headache, nausea, dizziness, paralysis and even death.
Asthma may be attributed to
(d) Asthma is an allergic condition in which the tissue surrounding the bronchioles of the lungs swell up and compress the bronchioles thus causing difficulty in breathing. This allergy mainly involves IgE antibodies and chemicals like histamine and serotonin from the mast cells.
Blood analysis of a patient reveals an unusually high quantity of carboxyhaemoglobin content. Which of the following conclusions is most likely to be correct?
The patient has been inhaling polluted air containing unusually high content of
(c) Carbon monoxide combines with \(\mathrm{Hb}\) far more readily than \(\mathrm{O}_2\) ( \(\mathrm{CO}\) has about 200 times greater affinity for \(\mathrm{Hb}\) as compared to \(\mathrm{O}_2\) ), forming a relatively stable compound carboxyhaemoglobin. This causes low supply of \(\mathrm{O}_2\) to the body cells leading to headache, nausea, dizziness, paralysis and even death.
During winter a person died during sleep, the room was closed and a container with burnt charcoal was found in the room. What may be the possible reason of his death?
(b) Charcoal on burning produces carbon monoxide (CO). \(\mathrm{CO}\) has about 200 times more affinity for \(\mathrm{Hb}\) than \(\mathrm{O}_2\). On combining with \(\mathrm{Hb}\), it forms a stable compound carboxyhaemoglobin. Because of this compound, \(\mathrm{Hb}\) cannot carry sufficient \(\mathrm{O}_2\) to the tissues ultimately leading to death.
Refer to the given graph and select the correct options for the questions that follow.
Blood can combine with almost ____ of oxygen if the haemoglobin is 100 percent saturated.
(c)
Refer to the given graph and select the correct options for the questions that follow.
Which of these is incorrect regarding A and B in the given graph?
(a)
Refer to the given graph and select the correct options for the questions that follow.
Which of these is correct regarding D, E and F areas in the graph?
(d) D – Venous blood during exercise
E – Normal venous blood
F – Normal arterial blood
Refer to the given graph and select the correct options for the questions that follow.
How much oxygen will be released to the tissues by blood on passing from lungs to tissues?
(c) \(5 \mathrm{~mL}\) of \(\mathrm{O}_2 / 100 \mathrm{~mL}\) of blood is released to tissues by blood as it passes from lungs to tissues.
Refer to the given graph and select the correct options for the questions that follow.
During strenuous exercise, the muscle interstitial fluid \(\mathrm{pO}_2\) falls to \(20 \mathrm{~mm} \mathrm{Hg}\). The oxygen delivered by blood that passes through the exercising muscle tissues will be
(c) The given graph shows the relationship between partial pressure of oxygen with the amount of oxygen that can bind with haemoglobin. The \(\mathrm{pO}_2\) of the air within alveoli is about \(100 \mathrm{~mm}\) \(\mathrm{Hg}\). As the blood travels through the systemic blood capillaries, oxygen leaves the blood and diffuses into the tissues. Consequently, the blood that leaves the tissues in the veins has a \(\mathrm{pO}_2\) that is decreasing (in a resting person) to about \(40 \mathrm{~mm} \mathrm{Hg}\). Therefore, A depicts oxygenated blood and B depicts systemic blood.
The steep portion of the curve from 60 down to \(20 \mathrm{~mm} \mathrm{Hg}\) is ideal for unloading oxygen in the tissue, i.e., for a small decrease in \(\mathrm{pO}_2\) (due to diffusion of oxygen) a large quantity of oxygen can be unloaded to the peripheral tissue capillary. During strenuous exercise, the muscles accelerated metabolism uses more oxygen from the capillary blood and thus decreases the venous blood \(\mathrm{pO}_2\) – for example the \(\mathrm{pO}_2\) of the venous blood could drop to \(20 \mathrm{~mm}\) \(\mathrm{Hg}\). Hence, \(D, E\) and \(F\) shows venous blood in exercise, normal venous blood and normal arterial blood respectively.
As we know, in the resting person, the \(\mathrm{pO}_2\) of tissues is \(40 \mathrm{~mm} \mathrm{Hg}\), which is favourable for oxygen diffusion from arterial blood to the tissues. Oxygen unloaded to the tissues by arterial blood is \(5 \mathrm{~mL} / 100 \mathrm{~mL}\) of blood \((20 \mathrm{~mL}-15 \mathrm{~mL}=5 \mathrm{~mL} / 100 \mathrm{~mL}\), from the graph). During strenuous exercise, the muscle interstitial fluid \(\mathrm{pO}_2\) falls to \(20 \mathrm{~mm} \mathrm{Hg}\), so the oxygen that unload to the tissue is \(15 \mathrm{~mL} / 100 \mathrm{~mL}\) of blood, \((20-5) \mathrm{mL} / 100 \mathrm{~mL}=15 \mathrm{~mL} / 100 \mathrm{~mL}\), from the graph i.e., three times as much as normal.
Refer to the given figure and select the correct options for the questions that follow.
Which of these is incorrect regarding the given mechanism of breathing?
During expel of air from lungs the volume of thorax decreases as it recoils and the diaphragm pushes as it relaxes. The ribs and sternum are relaxed and arch downwards pushing the air out. So the correct answer is ” Ribs and sternum are raised”.
Refer to the given figure and select the correct options for the questions that follow.
In the given mechanism, diaphragm, sternum and intercostal muscles work together to ____ the thoracic volume and thereby pulmonary volume. This leads to ____ intra-pulmonary pressure to slightly ____ the atmospheric pressure, causing expiration. Select the correct sequence of words to complete the above paragraph.
(c) During inspiration, the contraction of external intercostal muscles lifts up the ribs and the sternum to increase thoracic volume. The given diagram shows expiration process. The relaxing diaphragm and intercostal muscles return to their normal positions which reduce the thoracic volume and thereby the pulmonary volume. This leads to an increase in intra-pulmonary pressure to slightly above the atmospheric pressure causing the expulsion of air from the lungs, i.e., expiration.
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